We Kanto Chemical launched asymmetric hydrogenation catalysts, which were discovered by NOYORI Molecular Catalysis Project of Exploratory Research for Advanced Technology (ERATO) by Japan Science and Technology Corporation (JST) and were developed by Exploitation and Application Study supported by JST.
These catalysts have both diphosphine and diamine ligands, and the catalyst performance is tunable by the choice of these chiral ligands. Chiral Ru catalysts with BINAP ligand have high reactivity and enantioselectivity for the reaction of ketones1 , but higher enantioselectivity is desirable for certain ketonic substrates.
We examined the structure of the catalysts, and the chiral Ru catalysts with 1,3-diphosphine, XylSKEWPHOS [(2,4-bis(di-3,5-xylylphosphino)pentane)] were found to have higher enantioselectivity than the prototype BINAP catalysts.
Now we launch these asymmetric hydrogenation catalysts.
Product Information
| Product Name | Formula | Formula Weight | CAS No | Packing |
|---|---|---|---|---|
| Dibromo[(R,R)-2,4-bis(di-3’,5’-xylylphosphino)pentane]-[(R,R)-1,2-diphenylethanediamine]ruthenium(II){RuBr2[(R,R)-xylskewphos][(R,R)-dpen]} | C51H62Br2N2P2Ru | 1025.88 | 10535-68 | 100mg |
| 10535-95 | 500mg | |||
| Dibromo[(R,R)-2,4-bis(di-3’,5’-xylylphosphino)pentane]-[(S)-1,1-bis(p-methoxyphenyl)-2-isopropyl-1,2-ethanediamine]-ruthenium(II){RuBr2[(R,R)-xylskewphos][(S)-daipen]} | C56H72Br2N2O2P2Ru | 1128.01 | 10537-68 | 100mg |
| 10537-95 | 500mg | |||
| Dibromo[(S,S)-2,4-bis(di-3’,5’-xylylphosphino)pentane]-[(S,S)-1,2-diphenylethanediamine]ruthenium(II){RuBr2[(S,S)-xylskewphos][(S,S)-dpen]} | C51H62Br2N2P2Ru | 1025.88 | 10536-68 | 100mg |
| 10536-95 | 500mg | |||
| Dibromo[(S,S)-2,4-bis(di-3’,5’-xylylphosphino)pentane]-[(R)-1,1-bis(p-methoxyphenyl)-2-isopropyl-1,2-ethanediamine]-ruthenium(II){RuBr2[(S,S)-xylskewphos][(R)-daipen]} | C56H72Br2N2O2P2Ru | 1128.01 | 10538-68 | 100mg |
| 10538-95 | 500mg |
Related Product
Asymmetric Hydrogenation Catalysts
Chiral Ligands
XYLSKEWPHOS CATALYSTS